Efficacy of dexmedetomidine mixed with ropivacaine for brachial plexus block in patients undergoing upper limb surgery: a meta-analysis
10.3760/cma.j.issn.0254-1416.2018.06.017
- VernacularTitle:右美托咪定混合罗哌卡因用于上肢手术患者臂丛神经阻滞的有效性:meta分析
- Author:
Nana ZHU
1
;
Dao XIANG
;
Lin ZHU
;
Yanan CAO
;
Xueping HAN
;
Wei ZHANG
;
Zhentao SUN
Author Information
1. 450000,郑州大学第一附属医院麻醉科
- Keywords:
Dexmedetomidine;
Amides;
Brachial plexus;
Nerve block;
Meta analysis
- From:
Chinese Journal of Anesthesiology
2018;38(6):703-706
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically review the efficacy of dexmedetomidine mixed with ropivacaine for brachial plexus block in the patients undergoing upper limb surgery.Methods Medline,PubMed,Embase,Web of Science,Weipu,Wanfang,Zhiwang databases were searched for randomized controlled trials involving the efficacy of dexmedetomidine mixed with ropivacaine for brachial plexus block in patients undergoing upper limb surgery from the date of database establishment up to July 2017,and the trials were published in Chinese or in English.Evaluation indexes included onset time and duration of sensory and motor blocks and analgesia time when used for brachial plexus block.Trials were selected and data were extracted independently by 2 investigators,and meta-analysis was conducted using the Cochrane Collaboration's RevMan 5.3 software.Results Twelve randomized controlled trials were included in our metaanalysis.Compared with control group,the onset time of sensory and motor blocks was significantly shortened,the duration of sensory and motor blocks was prolonged,and analgesia time when used for brachial plexus block was prolonged in dexmedetomidine group (P＜0.01).Conclusion Dexmedetomidine mixed with ropivacaine can be effectively used for brachial plexus block in the patients undergoing upper limb surgery.
