Effect of early continuous renal replacement therapy on the prognosis of urosepsis
10.3760/cma.j.issn.1000-6702.2018.z1.020
- VernacularTitle:早期持续性肾脏替代治疗对尿源性脓毒血症预后的影响
- Author:
Haimin ZHANG
1
;
Bo PENG
;
Guangchun WANG
;
Wei LI
;
Wenyu GU
;
Xudong YAO
;
Junhua ZHENG
Author Information
1. 同济大学附属第十人民医院泌尿外科
- Keywords:
Continuous renal replacement therapy;
Urinary sepsis;
Upper urinary tract calculi;
Endoscopic surgery;
Prognosis
- From:
Chinese Journal of Urology
2018;39(z1):50-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of early continuous renal replacement therapy on the prognosis of urinary sepsis after surgery for upper urinary tract calculi.Methods The clinical data of 59 patients with urinary sepsis after surgery for upper urinary tract calculi were retrospectively analyzed.In 59 patients with urinary sepsis,9 patients with early persistent renal replacement therapy were selected as the experimental group and 50 patients without early continuous renal replacement therapy as the control group. The age,sex ratio,diabetes,hypertension,the average operation time were no significant difference(P>0.05).Preoperative urinary tract infection,the experimental group preoperative urinary tract infection was significantly higher than the control group(77.8% vs.32.0%,P<0.05).In the results of preoperative urine culture positive ratio,the experimental group was also significantly higher than the control group,the difference was statistically significant(P<0.05).The changes of prognostic factors in patients with or without continuous renal replacement therapy were analyzed.Results In terms of the changes of postoperative laboratory results,the decrease of procalcitonin(PCT),C-reactive protein,white blood cell count and neutrophil ratio in the experimental group was significantly larger than that in the control group, and the difference was statistically significant;on the increase of hemoglobin,platelet count,fibrinogen,the standard bicarbonate level from blood gas analysis in the experimental group increased significantly more than the control group,the difference between the two groups were statistically significant.Conclusions Early renal replacement therapy in patients with urinary sepsis after upper urinary tract calculi surgeries can improve the prognosis of patients.
