The abnormalities demonstrated by spine MRI indicate the possibility of etiology for refractory lower urinary tract symptoms in female patients
10.3760/cma.j.issn.1000-6702.2018.11.004
- VernacularTitle:女性顽固性下尿路症状患者的脊髓神经系统异常及其病因学意义
- Author:
Libo LIU
1
;
Peipei ZHANG
;
Qing LING
;
Zongbiao ZHANG
;
Peng CAO
;
Lei XU
;
Shengfei XU
;
Hailang LIU
;
Yong ZHANG
;
Xiaoyi YUAN
;
Liang WANG
;
Weimin YANG
;
Guanghui DU
Author Information
1. 华中科技大学同济医学院附属同济医院泌尿外科
- Keywords:
Female;
Lower urinary tract symptoms;
Spinal nerve system;
Magnetic resonance imaging;
Urodynamics;
Diagnosis
- From:
Chinese Journal of Urology
2018;39(11):814-818
- CountryChina
- Language:Chinese
-
Abstract:
Objective To approach the spine MRI features and its possibility of etiology for refractory lower urinary tract symptoms(LUTS) in female patients.Methods We conducted prospectively a cross sectional description study of female patients with refractory LUTS during January 16 through March 27 in 2017 based on a urologist's outpatient work.The including criteria were adult female patients with refractory LUTS which defined as having LUTS more than three months and having poor response to behavior therapy and medication treatment.The excluding criteria were patients having evidence of infection,tumor,stone in urinary tract,any central nerve system diseases,or any other diseases may potentially producing LUTS.Data collected included patients demographic information,main complains,present disease features,disease history,physical examination,urine routine,urodynamic study and spine MRI.The characteristics of clinical manifestation,urodynamic study and spine MRI were analyzed.Results During the time span of study,totally 70 cases had been diagnosed as having refractory LUTS and had qualified data of clinical recordings,urodynamic study and spine MRI.Among these 70 cases,63 (90.9％) had storage phase symptoms,11 (15.7％) had voiding phase symptoms,8 (11.4％) had postmicturition symptoms,12 (17.1％) also had disorders in defecating,45 (64.3％) had pain in lower abdomen or pelvic region.69 cases (98.6％) had urodynamic disorders,33 (47.1％) had oversensitivity of bladder,12 (17.1％) had smaller bladder volume,16(22.9％) had detrusor overactivity,15 (21.4％) had bladder outlet obstruction,39(55.7％) had detrusor underactivity.69 cases(98.6％)had spine MRI abnormalities,54(77.1％) had sacral nerve lesions,49 (70.0％) had cervical lesions,48 (68.6％) had lumbar lesions,4 had thorathic lesions.Conclusions The present study revealed extraordinary high prevalence of abnormality in urodynamic parameters and spine MRI in female patients with refractory LUTS,which implies possibility that the refractory LUTS are caused by lesions in spinal nerve system.
