Prospective randomized controlled trial of two ureteroileal anastomosis: split-cuff nipple vs.direct anastomosis
10.3760/cma.j.issn.1000-6702.2018.07.005
- VernacularTitle:劈开乳头式与直接吻合式输尿管-肠道新膀胱吻合方法的前瞻性临床随机对照研究
- Author:
Hao LIU
1
;
Wang HE
;
Xinxiang FAN
;
Hao YU
;
Yiming LAI
;
Tianxin LIN
;
Wenlian XIE
;
Yousheng YAO
;
Chun JIANG
;
Jinli HAN
;
Hai HUANG
;
Jian HUANG
Author Information
1. 中山大学孙逸仙纪念医院泌尿外科
- Keywords:
Bladder cancer;
Ureteroileal anastomosis;
Split-cuff nipple;
Direct
- From:
Chinese Journal of Urology
2018;39(7):495-499
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare split-cuff nipple and direct ureteroileal anastomosis during ureteroileal anastomosis.Methods Between December,2014 and March,2017,a prospective randomized study was conducted on 70 patients who underwent radical cystectomy and urinary diversion.In every patient,both ureters were randomized to be implanted using an antireflux,split-cuff nipple technique (group A) or a reflux,direct technique (group B).After pelvic lymph node dissection and radical cystectomy,a Mshape orthotopic ileal neobladder was constructed and two ureters were implanted with single-J tubes placed for 10-12 days.For split-cuff nipple technique,a 0.5 cm longitudinal incision in the ureter was made,and the ureteral wall was turned back on itself,construction a nipple.The cuff was stabilized at the corners with sutures.The ureter was then placed into the bowel with 0.5 cm nipple.The ureter was sutured to the full thickness of the bowel wall with interrupted 4-0 PDS.For direct technique,a 0.5 cm incision in the ureter was made,the full thickness of the ureter was sewn to the mucosa of the bowel.Results 70 patients were enrolled in the study,63 males and 7 females,(62.5 ± 10.4) years old.Over a median follow-up of 13.2 months,one patients had bilateral anastomosis stricture 3 months after operation,1 patient in group A had stricture 6 months after operation,2 patients in group B had stricture 6 and 12 months after operation,respectively.Six patients (8.6％) in group A found reflux compared with 21 patients (30.0％) in group B (P =0.004).The reflux pressure was (23.5 ± 9.0) cmH2O and (15.5 ± 4.9) cmH2O in group A and group B (P =0.042),respectively.The GFR of group A was (38.1 ± 7.6) ml/min compared with (38.6 ± 12.9) ml/min in group B at 12 months after operation.One patient in group A and four patients in group B had acute nephropyelitis.Four patients in group A had renal stones formation compared with 1 patients in group B.The time of anastomosis was (8.8 ± 3.5) minutes and (6.7 ± 1.5) minutes (P =0.037) for group A and group B,respectively.The patients in both groups had no urine leakage.Conclusion Compared with direct technique,split-cuff nipple technique had lower reflux rate,higher antireflux pressure and longer anastomosis time than direct technique.
