Comparative analysis of diagnostic application of perfusion imaging with DWI, 3D-TOF MRA and 3D-ASL in senile ischemic cerebrovascular diseases
10.3760/cma.j.issn.0254-9026.2018.08.003
- VernacularTitle:磁共振弥散加权成像和三维时间飞跃法血管成像及三维动脉自旋标记在老年人缺血性脑血管病中的应用
- Author:
Yong CUI
1
;
Zhiyan ZHENG
;
Ling HUANG
;
Lin SHEN
Author Information
1. 250033,山东大学第二医院医学影像中心
- Keywords:
Brain ischemia;
Diffusion magnetic resonance imaging;
Imaging,three-dimensional
- From:
Chinese Journal of Geriatrics
2018;37(8):847-850
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of magnetic resonance diffusion weighted imaging(DWI),3D time of flight magnetic resonance angiography(3D-TOF MRA),and 3D arterial spin labeled MR perfusion imaging(3D-ASL)in the senile ischemic cerebrovascular diseases.Methods Ninety patients with acute cerebral infarction and 69 with transient ischemic attack were retrospectively analyzed based on data of DWI,3DTOF MRA and 3D-ASL MRI.Additionally,60 healthy individuals were recruited as a control group.SPSS 21.0 statistical software was used.Results In 90 acute cerebral infarction(ACI)group,the 3D-ASL MRI showed hypoperfusion in 85 patients,hyperperfusion in 2 patients,and no apparently perfusion abnormality in 3 patients.In 85 hypoperfusion patients,the average hypoperfusion area showed by 3D-ASL MRI was(2 543±1 133)mm2,which was higher than the area of high signal in DWI(817±413) mm2 (P＜0.01),with ASL＞DWI in 83 cases and ASL≈DWI in 2 cases.In 69 transient ischemic attack patients,25 patients had artery stenosis and abnormal ASL,11 patients had artery stenosis and normal ASL,17 patients had normal vascular and abnormal ASL,15 had normal vascular and normal ASL.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value were higher in 3D-TOF MRA combined with 3D-ASL than in their individual inspection(x2=10.35,P＜0.01,P＜0.05),and the rates of missed diagnosis and misdiagnosis were lower in 3D-TOF MRA combined with 3D-ASL than in their individual inspection (x2 =4.93,P ＜ 0.05).Conclusions ASL,MRA,and DWI can =reflect the different characteristics of the senile ischemic cerebrovascular diseases,and should be used as the standard sequence in geriatric neurology to provide more comprehensive information for the diagnosis and treatment of senile ischemic cerebrovascular disease.
