Influence of metabolic syndrome on the prognosis of atrial fibrillation treated with catheter ablation in elderly patients
10.3760/cma.j.issn.0254-9026.2018.06.014
- VernacularTitle:代谢综合征对老年心房颤动患者导管消融预后的影响
- Author:
Guodong CHANG
1
;
Xuesheng XU
;
Hongwei ZHANG
;
Yingwei CHEN
;
Xiaojie CHEN
;
Xule WANG
;
Zhanying HAN
;
Chunguang QIU
;
Weihua GUO
Author Information
1. 476000,商丘市第一人民医院心内科
- Keywords:
Atrial fibrillation;
Catheter ablation;
Metabolic syndrome X
- From:
Chinese Journal of Geriatrics
2018;37(6):666-669
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the influence of metabolic syndrome(MS)on the success rate of catheter ablation for the treatment of atrial fibrillation (AF)in the elderly. Methods A retrospective study included a total of 221 aged patients with AF who underwent AF ablation for the first time. The patients were divided into two groups :an MS group(n＝72)and a control group(without MS)(n＝149) . The MS group had a mean age of (67.1 ± 5.2) years ;the control group had a mean age of (68.3 ± 5.7) years. Forty-six patients in the MS group and 105 patients in the control group experienced paroxysmal atrial fibrillation. Prognoses in two groups were compared at the end of the follow-up. Results At the end of the follow-up ,the success rates of the procedure in the MS group and the control group were 37.5%(n ＝ 27)and 51.7%(n ＝ 77) ,respectively (χ2＝ 3.917 ,P ＝ 0.049) .Recurrence happened in 19 patients of the MS group and 28 patients of the control group ,and they underwent a repeat ablation. The overall success rates after the last ablation in the two groups were 51.4%(n＝37)and 65.8%(n＝98) ,respectively (χ2＝4.224 ,P＝0.034).In the multivariable model adjusted for risk factors ,MS(HR＝1.42 ,95% CI :1.11-1.64 ,P＝0.033)and left atrial diameter(HR＝ 1.83 ,95% CI :1.27-3.19 , P ＝ 0.017 ) were independent predictors for recurrence. Conclusions MS can affect the success rate of catheter ablation for AF in elderly patients and the effect remains even after the procedures are repeated
