Association between body mass index and cardiovascular events in elderly hypertensive patients
10.3760/cma.j.issn.0254-9026.2018.05.004
- VernacularTitle:老年高血压患者体质指数对心血管事件的影响
- Author:
Juanjuan DU
1
;
Fang YUAN
;
Ping LUO
;
Lixia WANG
Author Information
1. 河南省人民医院心血管内科
- Keywords:
Hypertension;
Body mass index;
Factor analysis,statistical
- From:
Chinese Journal of Geriatrics
2018;37(5):501-505
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine the association between body mass index (BMI)and cardiovascular events in elderly hypertensive patients.Methods A total of 2267 elderly(age≥65) hypertensive patients undergoing long-term physical examination at Henan Province People's Hospital were included in this cohort study,and were divided into three groups:an underweight group(BMI≤ 18.4 kg/m2,n=125),a normal group(BMI=18.5-23.9 kg/m2,n=912),an overweight group(BMI=24.0 27.9 kg/m2,n=884),and an obesity group(BMI≥28.0 kg/ m2,n=346)for a six-year follow up period.The incidences of cardiovascular events were collected and analyzed for all groups.The Cox proportional hazards regression model was used to analyze all possible risk factors for all-cause deaths and cardiovascular events.Results There were 2 267 patients,including 1 260 male and 1 007 female patients,with a mean age of(75.7 ± 6.1)years.The Cox proportional hazards regression model showed that being underweight(BMI≤18.4 kg/m2)was a risk factor with a 1.8 times higher risk for all cause death and a 1.5 times higher risk for cardiovascular death than having a normal weight(RR=1.8,95 ％ CI:1.3-2.6;RR=1.5,95％ CI:1.3-1.7).Being overweight (BMI=24 27.9 kg/m2)was a protective factor with a 0.6 times lower risk for all-cause death and a 0.7 times lower risk for cardiovascular death,compared with the normal group (RR=0.6,95％ CI:0.5-0.8;RR=0.7,95％ CI:0.6-0.9).Obesity(BMI≥28.0kg/m2)was a protective factor for cardiovascular death with a lower relative risk of 0.9,compared with the normal group(RR=0.9,95％CI:0.9-1.0).Conclusions Paradoxically,being overweight is associated with a low mortality and a favorable cardiovascular prognosis,whereas being underweight carries a poor prognosis in elderly hypertensive patients.
