The therapeutic effects of stent retriever-based thrombectomy on acute ischemia stroke in patients aged 80 years and over
10.3760/cma.j.issn.0254-9026.2018.02.007
- VernacularTitle:80岁及以上老年急性缺血性卒中患者支架机械取栓的疗效
- Author:
Yimin DENG
1
;
Feng GAO
;
Xuan SUN
;
Ligang SONG
;
Lian LIU
;
Dapeng MO
;
Ning MA
;
Zhongrong MIAO
Author Information
1. 100050,首都医科大学附属北京天坛医院神经病学中心首都医科大学附属北京天坛医院介入神经病学科 国家神经系统疾病临床医学研究中心
- Keywords:
Stroke;
Thrombectomy
- From:
Chinese Journal of Geriatrics
2018;37(2):143-147
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and therapeutic effects of stent retriever-based thrombectomy (SRT) on acute ischemic stroke (AIS) in patients aged 80 years and older.Methods A cohort of 157 AIS patients hospitalized in Capital Medical University Affiliated Beijing Tiantan Hospital were selected for SRT from January 2016 to May 2017.Based on the age,all patients were divided into two groups:groups aged ＜ 80 years and ≥ 80 years.Baseline information including gender,the Modified Rankin Scale (mRS) score,past medical history,smoking history,preoperative National Institutes of Health Stroke Scale (NIHSS),the Alberta Stroke Program Early CT Scores (ASPECTS),intravenous thrombolysis and clinical outcomes were compared between two groups.The informations related to the operation,including time from onset to hospital,door-to-needle puncture time,door-to-recanalization time,SRT complications (symptomatic cerebral hemorrhage,mortality) and good outcome,were compared between two groups.Logistic regression analysis was used to determine whether the age of 80 years and over was a risk factor for adverse prognosis after SRT.Results There were 130 patients in the group ＜ 80 years of age,and 27 patients in the group ≥80 years.No significant differences were found in baseline information between the two groups (all P＞ 0.05).In addition,there were no significant differences in the proportions of the operative information,complications of SRT and the good outcome (all P＞0.05).Furthermore,advanced age (≥80 years) was not a risk factor for adverse outcome after SRT (OR =0.738,95％ CI:0.300-1.813).Conclusions Stent retriever-based thrombectomy is safe and beneficial for patients with acute ischemic stroke,even in patients aged 80 years and over.
