Relationship between blood uric acid and total carotid plaque burden in elderly patients with non-dialysis dependent chronic kidney disease
10.3760/cma.j.issn.0254-9026.2018.01.006
- VernacularTitle:血尿酸与老年慢性肾脏病非透析患者颈动脉斑块总积分的相关性分析
- Author:
Fangfang HU
1
;
Yong DANG
;
Yong WANG
;
Xiaoyan LI
;
Bo GAO
;
Huina CHEN
Author Information
1. 455000,安阳市人民医院肾内科
- Keywords:
Renal insufficiency,chronic;
Carotid artery diseases;
Uric acid
- From:
Chinese Journal of Geriatrics
2018;37(1):24-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between blood uric acid levels and total burden scores(TBS)of carotid plaques in elderly patients with non-dialysis dependent chronic kidney disease(CKD). Methods Seventy-seven elderly patients with non-dialysis dependent CKD were included.All clinical data were collected,and stepwise multiple linear regression was conducted to determine independent factors for TBS of carotid plaques in elderly patients with non-dialysis dependent CKD. Results Compared with the control group,TBS was significantly higher in the smoking group(P= 0.035),hypertension group(P= 0.014)and diabetic group(P= 0.041).In addition,correlation analysis showed that hemoglobin,low-density lipoprotein cholesterol,uric acid,C-react protein and estimated glomerular filtration rate were significantly correlated with TBS(all P<0.05).Furthermore,stepwise multiple linear regression analysis showed that TBS was markedly correlated with low-density lipoprotein cholesterol(P = 0.007,)and uric acid(P = 0.001). Conclusions Uric acid is an independent factor for TBS of carotid plaques in elderly patients with non-dialysis dependent CKD.
