Clinical value of combined magnetic resonance DWI and PWI in diagnosis of cerebral infarction at different stages
10.3969/j.issn.1009-0126.2018.06.004
- VernacularTitle:磁共振弥散加权成像联合灌注加权成像技术在诊断不同时期老年脑梗死的临床价值
- Author:
Guangmin LI
1
;
Jian YAO
;
Jiali ZHONG
;
Haomeng ZHU
;
Ruchen PENG
Author Information
1. 101149,首都医科大学附属北京潞河医院医学影像中心
- Keywords:
diffusion magnetic resonance imaging;
brain infarction;
magnetoencephalography;
collateral circulation
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(6):572-575
- CountryChina
- Language:Chinese
-
Abstract:
Objective To stuy the clinical value of combined DWI and PWI in diagnosis of cerebral infarction (CI) at different stages.Methods One hundred and sixty-eight elderly CI patients were divided into hyperacute phase group (n =32),acute phase group (n =64),subacute phase group (n=45) and chronic phase group (n=27).Their DWI and PWI parameters and abnormal brain regions were compared.Results The ADC on DWI for injured lateral brain tissue was significantly lower than that on DWI for unjured lateral brain tissue in hyperacute phase group and acute phase group (0.39±0.08 vs 0.83±0.03;0.32±0.07 vs 0.91±0.05,P＜0.01).However,the ADC on DWI for the injured lateral brain tissue was significantly higher than that on DWI for the uninjured lateral brain tissue in subacute phase group and chronic phase group (1.54±0.34 vs 0.85±0.07,2.01±1.29 vs 0.90±0.05,P＜0.01).The PWI showed that the CBV was smaller and the CBF was slower while the MTT and TTP were longer in CI patients at different stages.DWI＜PWI,DWI＞PWI,and DWI=PWI in abnormal signal region were more frequently detected in hyperacute phase,acute phase subacute phase and chronic phase respectively.Conclusion PWI can show ischemic penumbra while DWI can highlight infarct foci in CI patients.Combined PWI and DWI can display the CBF in CI patients at different stages,and can thus provide reference for the clinical treatment of CI.
