Mild cognition impairment in brain electrical activity
10.3969/j.issn.1009-0126.2018.05.016
- VernacularTitle:轻度认知功能障碍在脑活动状态下的脑电研究
- Author:
Daowen JI
1
;
Jing ZHANG
;
Huaying TAO
Author Information
1. 300192,天津市第一中心医院神经内科
- Keywords:
cognition disorders;
electroencephalography;
Alzheimer disease;
early diagnosis;
EEG Lemplc-Ziv complexity
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(5):512-516
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the characteristics of brain electrical signals in mild cognitive impairment (MCI) patients and healthy elderly volunteers in rest and task loading state.Methods Twenty MCI patients served as a MIC group and 22 sex-,age-and education-matched healthy volunteers served as a control group in this study.The patients were scored according to the MoCA,HADS,MMSE and CMS,their brain electrical signals in a different state were recorded with a digital EEG recording device,and their Lemple-Zie complexity (LZC) was computed on the MATLAB 7.04 platform and comparatively analyzed.Results The MQ value and MoCA,HADS,MMSE,CMS scores were significantly higher in control group than in MCI group (P＜0.01).The LZC value in left frontal region and left temporal region was significantly higher in control group than in MCI group in rest state (0.577±0.059 vs 0.545±0.067,0.576±0.061 vs 0.548±0.059,P＜0.05).The LZC value in right frontal region and right hemisphere was significantly lower in MCI group than in control group in brain electrical activity state (0.535±0.065 vs 0.559±0.033,0.541±0.064 vs 0.551±0.047,P＜0.05).The LZC value in left frontal region,left temporal region,left hemisphere was lower in control group than in MCI group (0.523±0.040 vs 0.547±0.070,0.547±0.048 vs 0.561±0.092,0.542±0.044 vs 0.557±0.067,P＜0.05).Conclusion The LZC value is lost in the left hemisphere but its functional compensation is present in the right and Left parietal lobe,left frontal lobe and right brain areas in MCI patients in a non-linear manner.
