Clinical curative effect of percutaneous transluminal angioplasty and simple pharmacotherapy for infrapopliteal artery ischemic disease
10.3969/j.issn.1009-0126.2018.05.003
- VernacularTitle:经皮腔内血管成形术与单纯药物治疗膝下动脉缺血临床疗效对比研究
- Author:
Xiao WANG
1
;
Shijun CUI
;
Yongquan GU
;
Shengjia YANG
;
Tao LUO
Author Information
1. 首都医科大学宣武医院血管外科
- Keywords:
angioplasty,transluminal,percutaneous coronary;
drug therapy;
lower extremity;
arteriosclerosis
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(5):458-461
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical curative effects of PTA and simple pharmacotherapy for intrapopliteal artery ischemic disease.Methods Seventy-three patients with intrapopliteal artery ischemic disease were divided into PTA group (n=37) and pharmacotherapy group (n=36).Their ABI,claudication distance,vascular patency,rest pain and amputation rate were recorded and analyzed with SPSS 22.0 at months 1,3,6,12,18 and 24 respectively before and after treat ment.The vascular patency and amputation rate were analyzed according to the Kaplan-Meier curve.Results The ABI was higher in PTA group than in pharmacotherapy group during the 1-24 months following up period after treatment,and was still higher in PTA group than in pharmacotherapy group at month 24 after treatment (0.640±0.238 vs 0.500±0.152,P=0.038).The claudication distance was shorter and the rest pain was milder in PTA group than in pharmacotherapy group at months 1 and 3,and at months 1-18 respectively (P＜0.05,P＜0.01).No significant difference was found in amputation-free survival curves between the two groups (Plogrank =0.618).Conclusion The symptom improvement of PTA is better than that of pharmacotherapy for patients with severe rest pain or severe intermittent claudication.
