Clinical characteristics of cognitive function in elderly acute stroke patients with chronic heart failure
10.3969/j.issn.1009-0126.2018.04.006
- VernacularTitle:伴有慢性心力衰竭的老年急性脑卒中患者认知功能临床特点分析
- Author:
Hua ZHANG
1
;
Peng YUAN
;
Shuping ZHANG
;
Shuiping LIU
;
Li WANG
;
Rong HU
Author Information
1. 100029,首都医科大学附属北京安贞医院神经内科
- Keywords:
heart failure;
stroke;
atrial fibrillation;
diabetes mellitus;
cognition disorders
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(4):358-362
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical characteristics of cognitive function in elderly acute stroke (AS) patients with CHF.Methods Two hundred and seventeen elderly AS patients with CHF were devided into HFrEF group (n=77),HFmrEF (n=46) and HFpEF group (n=94) according to their LVEF.Their clinical data (including baseline demographic data,history of disease,NIHSS score,MMSE score,MoCA score,responsible lesions) were recorded and analyzed.Results The SBP and total MoCA score were significantly lower while the incidence of persistant AF,DM and serum HbA1C level were significantly higher in HFrEF group than in HFmrEF group and HFpEF group (P<0.05,P<0.01).The incidence of left ventricular hypertrothy was higher in HFpEF group than in HFmrEF group and HFpEF group (P<0.01).The total incidence of cognitive impairment was 54.8% in 217 AS patients with CHF.Logistic regression analysis showed that persistant AF,SBP and DM were the risk factors for cognitive impairment (OR=2.757,P=0.017;OR=0.971,P=0.001;OR=2.293,P=0.031).Conclusion The incidence of cognitive impairment is rather high in elderly AS patients with CHF.Persistant AF,DM and SBP are the risk factors for cognitive impairment.Attention should thus be paid to the assessment of cognitive impairment in elderly AS patients with CHF.