Association between serum biochemical parameters and transient ischemic attack
10.3969/j.issn.1009-0126.2018.03.014
- VernacularTitle:短暂性脑缺血发作患者的血清生化指标的相关性研究
- Author:
Youping XUE
1
;
Yi LEI
;
Feng LIU
;
Muyang LI
;
Jianxin LIU
Author Information
1. 066000,秦皇岛军工医院检验科
- Keywords:
ischemic attack,transient;
homocysteine;
C-reactive protein;
hyperlipidemias
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(3):275-277
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the association between H cy,hs-CRP,IMA and transient ischemic attack (TIA).Methods One hundred and twenty-six TIA patients were divided into low risk group (n=42),moderate risk group (n=43) and high risk group (n=43) according to their AB-CD2 score with 20 healthy subjects undergoing physical examinarion served as control group.Their clinical data were recorded and their serum Hcy,IMA and hs-CRP levels were compared.Results The serum levels of TC,TG,LDL,Hcy,IMA and hs-CRP were significantly higher while those of HDL were significantly lower in low risk group,moderate risk group and high risk group than in control group (P＜0.05),in moderate risk group and high risk group than in low risk group (P＜0.05),and in high risk group than in moderate risk group (P＜0.05).The serumlevels of Hcy,hs-CRP and IMA were positively associated with ABCD2 score in TIA patients (r=0.36,r =0.31,r =0.24,P＜0.05) but not associated with each other (P＞0.05).Multivariate logistic regression analysis showed that hyperlidemia and Hcy were the risk factors for TIA (P＜0.05,P＜0.01).Conclusion Serum Hcy,hs-CRP,IMA levels are positively associated with AB-CD2 score.Hyperlipidemia and Hcy are the risk factor for TIA.Measurement of serum Hcy,hsCRP,IMA levels is beneficial to the assessment of TIA.
