Prevalence of hyperuricemia and its risk factors in elderly people undergoing physical examination in Yiyang District
10.3969/j.issn.1009-0126.2018.02.014
- VernacularTitle:益阳地区老年体检人群高尿酸血症患病率及相关危险因素分析
- Author:
Bingpo ZHU
1
;
Li FAN
;
Shijie LIN
;
Jinjin YAN
;
Fang XU
;
Xiang LIU
;
Min GUO
;
Qiaoling LIU
;
Cheng XU
Author Information
1. 413000,湖南益阳康雅医院健康管理中心
- Keywords:
hyperuricemia;
prevalence;
uric acid;
hyperlipidemias;
obesity
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(2):164-167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence of hyperuricemia and its risk factors in elderly people of Yiyang District,Hunan Province,China.Methods A total of 1363 elderly people undergoing physical examination in our hospital were divided into hyperuricemia group (n=245) and control group (n=1118).Their general clinical data were recorded and compared.The risk factors for hyperuricemia were analyzed.Results The age was significantly older,number of males was significantly larger,the serum TG,LDL-C,urea,UA levels and body height,BMI,SBP were significantly higher while the serum TC and HDL-C levels and Cr clearance rate were significantly lower in hyperuricemia group than in control group (P＜0.05,P＜0.01).Pearson correlation analysis showed that serum UA level was positively related with age,serum TG and urea level,BMI,SBP and DBP,but negatively related with Cr clearance rate and serum TC,LDL-C,HDL-C levels (P＜ 0.01).Binary logistic regression analysis showed that age,male gender,hyperlipidemia,and obesity were the independent risk factors for hyperuricemia after adjustment of age (OR=1.857,95 ％ CI:1.302-2.649,P=0.001;OR=1.866,95％CI:1.363-2.555,P=0.000;OR=2.214,95％ CI:1.716-2.856,P=0.000).However,serum HDL-C level and Cr clearance rate were the protective factors for hyperuricemia (OR =0.388,95 ％ CI:0.242-0.623,P =0.000;OR =0.948,95％CI:0.937-0.959,P=0.000).Conclusion The prevalence of hyperuricemia is rather high in elderly people of Yiyang Distric,Hunan Province,China,suggesting that the lifestyle of elderly people should be improved and hyperuricemia should be treated with appropriate drugs.
