Value of Lp (a) in risk assessment of patients with non ST-elevation acute coronary syndrome
10.3969/j.issn.1009-0126.2018.02.010
- VernacularTitle:脂蛋白(a)对非ST段抬高型急性冠状动脉综合征患者风险评估的价值
- Author:
Yang GU
1
;
Kun YU
;
Zhuo XU
;
Peibing GE
;
Xiwen ZHANG
Author Information
1. 223300,南京医科大学附属淮安第一医院心内科
- Keywords:
lipoprotein(a);
acute coronary syndrome;
hypertension;
diabetes mellitus;
troponin
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2018;20(2):149-152
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of Lp (a) in risk assessment of patients with NSTE-ACS.Methods Eighty NSTE-ACS patients were divided into elderly NSTE-ACS group (n=58) and non elderly NSTE-ACS group (n=22) with 22 elderly patients with their coronary artery stenosis ＜ 50％ served as a control group.The relationship of serum Lp (a) level with Gensini score and GRACE risk score was analyzed.Results The incidence of hypertension and DM was significantly higher,the smoking history was significantly longer,the serum LDL-C and FBG level,Gensini score and GRACE risk score were significantly higher in elderly NSTE-ACS group than in control group (P＜0.05).The age was significantly older and the GRACE risk score was significantly higher in elderly NSTE-ACS group than in non elderly NSTE-ACS group (P＜0.05).The Gensini score and GRACE risk score were positively related wtih the serum Lp (a) level (r=0.494,P＜ 0.01;r=0.432,P＜0.01).Serum Lp (a) level was an independent risk factor for NSTE-ACS (P＜0.01).Conclusion Serum Lp (a) level is closely related with the severity and outcome of NSTE-ACS,indicating that serum Lp (a) level can be used as a predictor of risk assessment in NSTE-ACS patients.
