Surgical Management of Aortic Insufficiency in Behcet's Disease.
- Author:
Gyung Hwan KIM
1
;
Ki Bong KIM
;
Won Gon KIM
;
Joo Hyun KIM
;
Hyuk AN
Author Information
1. Department of Thoracic and Cardiovascular Surgery, College of Medicine Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Behcet's disease;
Aortic valve, insufficiency
- MeSH:
Allografts;
Autografts;
Behcet Syndrome;
Diagnosis;
Endocarditis;
Female;
Follow-Up Studies;
Heart;
Humans;
Male;
Prognosis;
Rupture;
Transplants;
Young Adult
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2000;33(5):391-397
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Cardiac involvement of Behcets disease is very rate, however, the prognosis of Behcet disease depends on cardiovascular complications. In this article, we described surgical treatment of aortic insufficiency with Behcets disease. MATERIAL AND METHOD: From March 1986 to February 1998, we operated on 10 patients of aortic insufficiency with Behcets disease. Male to female ratio was 8 to 2, and age ranged from 21 to 40 years(mean 32.8 years). There were 8 patients with evidence of Behcets disease and another 2 patients had some suspicious findings of Behcets disease(i.e., prosthetic value dehiscence, hypertrophied aortic wall). Adequate preoperative medical treatment for Behcets disease was done in 3 patients. RESULT: We performed 24 open heart surgeries in 10 patients. Redo value replacements using prosthetic valves were done in 4 patients. Among them, 2 patients were operated on for a second redo valve replacement and one of them operated on for a 4th and 5th operation because of recurrent paravalvular leakage. These 4 patients expired. 1 patient who had undergons tissue value replacement is alive. 1 patient who underwent Cabrol operation expired dut to rupture of graft anastomosis site. We used homografts in 3 patients. In 2 of them, we performed aortic root replacement and subcoronary valve replacement in another patient. The patient who underwent subcoronary valve insertion had remnant aortic insufficiency, so we are closely observing him. We also performed Ross operation in a 24 year old female who suffered severs aortic insufficiency and endocarditis after aortic valvuloplasty. 5 patients are alive and mean follow up duration is 49.0 months. Among them, we used homografts or sutografts in 4 patients. We could observe excellent clinical results in the patients who underwent aortic root replacement using homograft and they were treated medically for Behcets disease. CONCLUSIONS: We concluded that adequate preporative diagnosis, clinical suspicion, and periopertive medical treatment for Behcets disease are very important for the result of surgical management of aortic insufficiency with Behcets disease. The use of homograft or autograft was helpful for the healing of anastomosis site and we should carefully observe the long term follow up results.
