Radionuclide functional and molecular imaging in rapid eye movement sleep behavior disorder
10.3760/cma.j.issn.2095-2848.2018.05.016
- VernacularTitle:快速眼动睡眠期行为障碍的核素显像研究进展
- Author:
Xianhua HAN
1
;
Ping WU
;
Chuantao ZUO
Author Information
1. 复旦大学附属华山医院PET中心
- Keywords:
REM sleep behavior disorder;
Radionuclide imaging;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2018;38(5):367-370
- CountryChina
- Language:Chinese
-
Abstract:
Rapid eye movement sleep behavior disorder (RBD) is a condition characterized by rap id eye movement sleep without atonia and with complex behaviors associated with dreams.Numerous studies have revealed that idiopathic RBD is the prodromal manifestation of neurodegenerative disorders,especially those mediated by α-synuclein.The structural and functional imaging of RBD,including transcranial sonog raphy (TCS),MRI,SPECT,PET,are increasingly becoming the hot issues.This review summarizes the radionuclide imaging in RBD,which may be one of the most promising modalities to detect the biomarkers for early diagnosis of neurodegenerative disorders.
