Research progress in imaging agents targeting Aβ and Tau protein in Alzheimer's disease
10.3760/cma.j.issn.2095-2848.2018.04.018
- VernacularTitle:Aβ类和Tau蛋白类分子探针在阿尔茨海默病中的研究进展
- Author:
Zhanpin ZHU
1
;
Hong ZHU
Author Information
1. 210002,南京军区南京总医院核医学科
- Keywords:
Alzheimer disease;
Molecular probes;
Amyloid;
Tau proteins;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2018;38(4):291-294
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is a neurodegenerative disease,which is insidious onset and progressive.The pathological features of AD include senile plaques composed of amyloid β (Aβ) and neurofibrillary tangles composed of Tau protein.Aβ and Tau protein targeted imaging agents,which make a non-invasive and high specificity diagnosis,might be useful for early diagnosis,efficacy monitoring and drug evaluation for AD.This review summarizes the progress and clinical applications of those agents in AD.
