Fecal Transplantation using a Nasoenteric Tube during an Initial Episode of Severe Clostridium difficile Infection.
- Author:
Yong Duk JEON
1
;
Namki HONG
;
Jung Ho KIM
;
Se Hee PARK
;
Sung Bae KIM
;
In Ji SONG
;
Hea Won ANN
;
Jin Young AHN
;
Sun Bean KIM
;
Nam Su KU
;
Kyungwon LEE
;
Dongeun YONG
;
June Myung KIM
;
Jun Yong CHOI
Author Information
- Publication Type:Case Report
- Keywords: Fecal transplantation; Fecal microbiota; Clostridium difficile; Nasoenteric tube
- MeSH: Clostridium difficile*; Clostridium*; Incidence; Korea; Metronidazole; Mortality; Recurrence; Treatment Failure; Vancomycin
- From:Infection and Chemotherapy 2016;48(1):31-35
- CountryRepublic of Korea
- Language:English
- Abstract: The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
