Application of 123/131I-MIBG in the diagnosis and treatment of pediatric neuroblastoma
10.2967/jnumed.114.141424
- VernacularTitle:放射性碘标记MIBG在儿童神经母细胞瘤诊治中的应用
- Author:
Yanlei HUO
1
;
Danyang WANG
;
Hui WANG
;
Chao MA
Author Information
1. 200092,上海交通大学医学院附属新华医院核医学科
- Keywords:
Neuroblastoma;
Iodine radioisotopes;
3-Iodobenzylguanidine;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2017;37(3):173-176
- CountryChina
- Language:Chinese
-
Abstract:
As a type of neuroendocrine tumors,neuroblastoma (NB) is the most common extra-cranial solid tumor of childhood.123/131I-MIBG scintigraphy is a standard imaging modality in staging and evaluating therapeutic effect of pediatric NB with high accuracy.131I-MIBG treatment is effective for children with high-risk and relapsed/refractory NB.Combined with chemotherapy,stem cell transplantation,131I-MIBG treatment shows efficacy in decreasing the relapse of pediatric NB.This review summarizes the application of MIBG scintigraphy and 131I-MIBG treatment for pediatric NB.
