Biliary complications and recovery of liver function after liver transplantation from citizen's deceased donors versus standard criteria donors
10.3760/cma.j.issn.1007-8118.2018.07.002
- VernacularTitle:公民死亡器官捐献供肝与司法途径标准供肝移植术后胆道并发症和肝功能恢复情况比较
- Author:
Huaxiang WANG
1
;
Ruisheng KE
;
Yi JIANG
;
Fang YANG
;
Qiucheng CAI
;
Xinghua HUANG
;
Jianyong LIU
;
Dongmei YE
;
Aiping WU
Author Information
1. 厦门大学附属东方医院肝胆外科
- Keywords:
Liver transplantation;
Donation after citizen's deceased;
Standard criteria donors;
Liver function;
Biliary complications;
Propensity score matching(PSM)
- From:
Chinese Journal of Hepatobiliary Surgery
2018;24(7):437-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the biliary complications and recovery of liver function after liver transplantation from citizen's deceased donors (DCD) versus standard criteria donors (SCD).Method The clinical data of 269 patients who underwent orthotopic liver transplantation from January 2009 to December 2016 at the Fuzhou General Hospital were collected.197 livers were from SCD and 72 from DCD.Propensity score matching (PSM) was used to compare the biliary complications and recovery of liver function after liver transplantation in the two groups.Results PSM matched 61 pairs of patients.There were 10 (16.4％) and 8 (13.1％) biliary complications in the DCD and the SCD groups,respectively,with no significant difference between them (P ＞ 0.05).The recovery of liver function was significantly delayed in the DCD group when compared with the SCD group.The levels of ALT,AST,GGT and AKP in the DCD group were significant different on the postoperative first,third,fifth,seventh and fourteenth day (P ＜ 0.05).At 30 days after surgery,there was no significant difference in liver function between the two groups.Conclusions Liver grafts from DCD had a significant impact on the recovery of liver function.When compared with the SCD group,the DCD group recovered significantly slower in liver function.There was no significant increase in the incidence of biliary complications.
