Research progress on machine perfusion to reduce the incidence of non-anastomotic biliary stricture after liver trans-plantation
10.3760/cma.j.issn.1007-8118.2018.05.018
- VernacularTitle:机械灌注降低肝移植术后非吻合口胆管狭窄发生率的研究进展
- Author:
Zehong FANG
1
;
Xianpeng ZENG
;
Zhijian YANG
;
Qifa YE
;
Yanfeng WANG
Author Information
1. 武汉大学中南医院武汉大学肝胆疾病研究院武汉大学移植医学中心
- Keywords:
Live transplantation;
Donor;
Machine perfusion;
Non-anastomotic biliary strictures;
Complication
- From:
Chinese Journal of Hepatobiliary Surgery
2018;24(5):352-355
- CountryChina
- Language:Chinese
-
Abstract:
Liver transplantation has become the most effective treatment for end-stage liver diseases.Due to the shortage of organ,more and more extended criteria donors (ECD) grafts had been used,which expand the liver pool.However,a series of complications post transplantation were caused by ischemia,hypoxia,steatosis and so on.The non-anastomotic biliary strictures after liver transplantation is one of the major complications when the ECD donors was be used in clinic.The study on the protective effect of machine perfusion on liver donors is too numerous to list,and existing studies have found that MP can reduce the incidence of NAS after liver transplantation.This review provides an overview of the pathogenesis of NAS and the reduction incidence of NAS by MP.
