The clinical efficacy of Dyna computer tomography guided radiofrequency ablation combined immediately with transarterial chemoembolization to treat large solitary hepatocellular carcinomas
10.3760/cma.j.issn.1007-8118.2018.05.002
- VernacularTitle:Dyna计算机断层扫描在肝动脉化疗栓塞即时联合射频消融治疗孤立性大肝癌的应用价值
- Author:
Hongjun YUAN
1
;
Fengyong LIU
;
Xin LI
;
Yang GUAN
;
Maoqiang WANG
Author Information
1. 100853,解放军总医院介入放射科
- Keywords:
Carcinoma,hepatocellular;
Chemoembolization,therapeutic;
Radiology,interventional;
Dyna CT
- From:
Chinese Journal of Hepatobiliary Surgery
2018;24(5):294-298
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical efficacy of Dyna computer tomography (Dyna CT) guided radiofrequency ablation (RFA) followed immediately by transcatheter arterial chemoembolization (TACE) in the treatment of large solitary hepatocellular carcinomas (HCC),and to provide the basis for the rational use of Dyna CT.Methods A retrospective analysis was performed on 23 patients with a large solitary hepatocellular carcinoma (tumor diameter ≥5 cm) who were admitted to Chinese PLA General Hospital from January 2014 to October 2015 and treated with Dyna CT guided RFA followed immediately by TACE.After treatment,the success rate of the combined technique,the treatment time,the radiation dose received by the patient,the complication and the efficacy of the combined therapy were evaluated.Results The success rate of the combined technique was 100％.The treatment time was (45.3 ± 4.8) min.The radiation exposure dose was (730.5 ± 78.8) mGy.There was no serious complication after treatment.The complete remission rate of the targeted lesion was 91.3 ％ (21/23),the partial remission rate was 8.7 ％ (2/23).On follow-up,5 patients had died.The 6,12,18 month survival rates were 100％,81.5％ and 48.0％,respectively.Conclusions Dyna CT guided RFA for a large solitary HCC was efficacious and safe.The immediate combination of TACE with RFA provided a new alternative strategy for the treatment of a large solita-ry HCC.Dyna CT has important clinical values.
