Diagnosis and prognosis of solid pseudopapillary tumor of pancreas: an analysis of 68 patients
10.3760/cma.j.issn.1007-8118.2018.02.008
- VernacularTitle:胰腺实性假乳头状瘤诊疗及预后:68例分析
- Author:
Xun CHEN
1
;
Jinxue ZHOU
;
Qingjun LI
;
Kai WANG
;
Zhengzheng WANG
;
Xiangyu ZHAN
Author Information
1. 450008,郑州大学附属肿瘤医院肝胆胰腺外科
- Keywords:
Solid-pseudopapillary tumor of pancreas (SPTP);
Resection of pancreas and duodenum;
Excision of body and tail of pancreas;
Prognosis
- From:
Chinese Journal of Hepatobiliary Surgery
2018;24(2):100-103
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the diagnosis,treatment and prognosis of patients with solid-pseudopapillary tumor of the pancreas (SPTP).Methods The clinical and follow-up data of 68 patients with SPTP treated in the Affiliated Tumor Hospital of Zhengzhou University from January 2008 to March 2017 were retrospectively analyzed.Results There were 6 males and 62 females,with an average age +/-S.D.of (32.0 ± 12.0) years.The mean tumor size was (4.4 ±2.3) cm.The primary symptom was abdominal pain,and a pancreatic mass was subsequently detected.All the patients underwent surgical resection which included pancreaticoduodenectomy,duodenal preserving pancreatic head resection,distal pancreatectomy,middle pancreatectomy,local excision,resection of pancreatic tail plus splenectomy and distal pancreaticosplenectomy.Postoperative histopathological examination confirmed solid pseudopapillary tumor of the pancreas in all these patients.Twenty-one patients (30.9％) developed postoperative complications,which included pancreatic fistula in 12 patients (17.7％),hemorrhage in 2 patients (2.9％),pleural effusion in 2 patients (2.9％),incision infection in 3 patients (4.4％),and gastric emptying disorder in 2 patients (2.9％).There was no in-hospital mortality.The average length of hospital stay was (26.0 ± 10.0) days.Of the 57 patients (83.8％) who were followed-up (mean 38 months,range 3 to 114 months),11 patients developed postoperative indigestion and 2 patients diabetes.No patient developed tumor recurrence,metastasis and death.Conclusions SPTP is a low grade malignant tumor,which is found primarily in young women.The clinical characteristics are non-specific,and preoperative diagnosis is difficult.Excellent prognosis can be achieved with surgical resection which is the preferred treatment for SPTP.
