A clinical treatment strategy for ruptured hepatocellular carcinoma
10.3760/cma.j.issn.1007-8118.2017.12.002
- VernacularTitle:原发性肝细胞癌破裂出血临床治疗策略
- Author:
Wei BAO
1
;
Xinqi FAN
;
Yechuan XU
;
Canliang LU
;
Wei DAI
;
Zhilei LI
Author Information
1. 安徽医科大学第一附属医院肝胆胰外科
- Keywords:
Ruptured bleeding in hepatocellular carcinoma;
Prognosis;
Interventional therapy;
Resection;
Overall survival
- From:
Chinese Journal of Hepatobiliary Surgery
2017;23(12):805-808
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognoses of patients with ruptured hepatocellular carcinoma (HCC) after resection combined with interventional therapy.Methods This retrospective study was conducted on 50 consecutive patients with ruptured hepatocellular carcinoma treated from March 2013 to December 2016 in the First Affiliated Hospital,Anhui Medical University.The patients were divided into two groups according to the different therapies,they underwent:Group A resection after interventional therapy (n =20) and Group B interventional therapy after resection (n =40).The COX regression multivariate analysis was performed and the 1-year,2-year,3-year overall survival rates (OS) were calculated.Results The 3-year OS rates were significantly different (OS:34％ vs.0％,P =0.044).Multivariate survival analysis showed that age (HR 1.376,P ＜0.001,95％ CI 1.191 ～ 1.589) and blood transfusion (HR 1.001,P ＜ 0.05,95％ CI 1.000 ～ 1.003) were the two prognostic factors which affected OS rates of patients.Conclusions Combined surgical resection and interventional therapy was effective in treating patients with ruptured hepatocellular carcinoma.Resection after interventional therapy gave a better overall survival rate than interventional therapy after resection.
