Application of endoscopy-guided titanium clip placement in precision radiotherapy for early esophageal cancer
10.3760/cma.j.issn.1004-4221.2018.11.004
- VernacularTitle:内镜下钛夹标记在早期食管癌精确放疗中应用
- Author:
Lijun ZHAO
1
;
Jianfeng WU
;
Hong JI
;
Ming JIANG
;
Yatian LIU
;
Tingting WANG
;
Xue SONG
;
Lei HUANG
;
Jun ZHU
Author Information
1. 江苏省肿瘤医院&江苏省肿瘤防治研究所和南京医科大学附属肿瘤医院
- Keywords:
Esophageal neoplasm/radiotherapy;
Endoscopy;
Titanium clip
- From:
Chinese Journal of Radiation Oncology
2018;27(11):971-974
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application of the placement of titanium clips in the upper and lower tumor margins in precision radiotherapy for early esophageal cancer. Methods:Seventeen patients with early esophageal cancer underwent endoscopy-guided implantation of titanium clips to mark the upper and lower tumor margins. CT-based simulation was performed to delineate the gross tumor volume ( GTV) . The application value of this technology in precision radiotherapy was evaluated. Results:For all patients (including 13 cases with initial treatment and 4 patients requiring radiotherapy after endoscopic resection), the esophageal tumors were not explicitly displayed on CT and barium meal images and the GTV range could not be accurately determined. The esophageal tumors were marked by successful placement of at least one titanium clip in the upper and lower tumor margins. Subsequently, the esophageal tumors were successfully displayed on CT simulation and the target area was accurately delineated. No grade 3-4 adverse events, such as bleeding and perforation occurred. Conclusion Endoscopy-guided titanium clip placement is convenient and feasible for early esophageal cancer, which is of clinical significance for determining the target area of radiotherapy.
