A case of primary malignant uterine cervical Non-Hodgkin's lymphoma with breast involvement.
- Author:
Nae Yu KIM
1
;
In Sung CHO
;
Soo Jung GONG
;
Mee Ran LEE
;
Mee Ja PARK
;
Chun Hwa IHM
;
Jung Ae LEE
Author Information
1. Department of Internal Medicine, Eulji University School of Medicine, Daejon, Korea. lee982023@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Primary uterine cervical lymphoma;
Breast involvement
- MeSH:
Adult;
Antibodies, Monoclonal, Murine-Derived;
Biopsy;
Biopsy, Needle;
Breast;
Cervix Uteri;
Drug Therapy, Combination;
Female;
Fibroadenoma;
Formycins;
Humans;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, Non-Hodgkin;
Ribonucleotides;
Uterine Hemorrhage;
Rituximab
- From:Korean Journal of Medicine
2008;74(4):435-440
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary lymphoma arising from the uterine cervix has been rarely encountered, and breast involvement is rare because of the relative paucity of lymphoid tissue in the breast. A 32-year-old woman with a primary malignant lymphoma of the uterine cervix and breast involvement is reported. The patient presented with post-coital vaginal bleeding, and punch biopsy of the cervix revealed the diffuse large B cell type of malignant lymphoma. PET-scan was done for staging, and abnormal FDP uptakes were detected in a uterine cervical mass and breast nodule. Ultrasonography-guided needle biopsy was done for the breast mass, and 2 biopsied nodules revealed fibroadenoma and diffuse large B cell lymphoma. The patient (Ann Arbor stage IV) was treated with 6 cycles of combination chemotherapy with CHOP plus rituximab. The patient went into complete remission. Thereafter, 4500cGy pelvic irradiation was done for adjuvant therapy.