A case of primary effusion lymphoma.
- Author:
Kwan Mi PACK
1
;
Sang We KIM
;
Sang Do LEE
;
Yoon Ji KIM
;
Cheolwon SUH
;
Dong Kwan KIM
;
Dong Eun SONG
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swkim@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Primary effusion lymphoma;
Adenosine deaminase
- MeSH:
Abdomen;
Adenosine Deaminase;
Aged;
Biopsy;
DNA;
Dyspnea;
Exudates and Transudates;
Female;
Herpesvirus 8, Human;
HIV;
Humans;
Lung;
Lymph Nodes;
Lymphoma, B-Cell;
Lymphoma, Primary Effusion;
Physical Examination;
Pleura;
Pleural Effusion;
Pleurisy;
Pleurodesis;
Polymerase Chain Reaction;
Serologic Tests;
Thoracic Surgery, Video-Assisted;
Thorax
- From:Korean Journal of Medicine
2008;74(4):441-444
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 78-year-old woman was referred to this hospital because of exertional dyspnea for 2 weeks. Although she was treated with anti-tuberculous medication under the assumption that she had tuberculous pleuritis, her dyspnea continued. Physical examination revealed diminished breath sounds over the left lung field. Chest radiography showed a large left pleural effusion. The pleural effusion revealed malignant cell dominant exudates with a high adenosine deaminase level. Serological tests were negative for HIV. Computed tomography scan of the chest and abdomen showed pleural effusion, but no mass or pathological lymph nodes were detected. The biopsy specimen of the pleura was diagnosed as malignant B cell lymphoma with plasmacytoid features, suggesting a possibility of primary effusion lymphoma. Polymerase chain reaction assay of tumor was positive for HHV-8 DNA. She underwent pleurodesis during Video-Assisted Thoracic Surgery, and her dyspnea subsequently improved.
