Research progress in replanning during intensity-modulated radiotherapy for nasopharyngeal carcinoma

VernacularTitle:鼻咽癌IMRT再计划的研究进展
Author: Qun SHEN ¹ ; Li LUO ; Feng LIU ; Xuping XI
Author Information

1. 415003,常德市第一人民医院
Keywords: Nasopharyngeal neoplasm/intensity-modulated radiotherapy; Replanning
From: Chinese Journal of Radiation Oncology 2018;27(3):312-315
CountryChina
Language:Chinese
Abstract: Intensity-modulated radiotherapy(IMRT)is the first-line treatment for nasopharyngeal carcinoma currently. Previous studies have shown that regression of primary tumor and metastatic lymph nodes or a decrease in body weight causes the contour of normal organs and head-and-neck to shrink during the course of radiotherapy, which may lead to underdose in primary tumor and overdose in organs at risk (OARs)and then adversely affect treatment outcomes. Replanning during the course of radiotherapy can maintain the dose to target volume and reduce the exposure of OARs, which improves outcomes in some patients. For replanning during the course of IMRT, however, the advantages have not been widely recognized and there is still a long way to go before widely accepted timing and frequency of replanning are set up. Further studies are needed to figure out how to identify patients appropriate for plan modification.