Dose analysis of hippocampus in T3,T4nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
10.3760/cma.j.issn.1004-4221.2018.03.003
- VernacularTitle:T3、T4期鼻咽癌IMRT中海马受量相关性分析
- Author:
Zongwen SUN
1
,
2
;
Lei SHI
;
Yue KONG
;
Fenglei DU
;
Tieming XIE
;
Mengyuan CHEN
;
Ziyu ZHU
;
Yonghong HUA
;
Qiaoying HU
;
Xiaozhong CHEN
;
Yuanyuan CHEN
;
Ming CHEN
Author Information
1. 530021,苏州大学附属第二医院放疗科
2. 272100,济宁市第一人民医院肿瘤科
- Keywords:
Nasopharyngeal neoplasms/intensity-modulated radiotherapy;
Hippocampus
- From:
Chinese Journal of Radiation Oncology
2018;27(3):240-244
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the exposed dose of hippocampus(HC)of T3,T4nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy(IMRT). Methods The bilateral HCs were delineated and were divided into head(HH),body(HB)and tail(HT)for 62 nasopharyngeal carcinoma patients treated with IMRT.The dose parameters of HC were then analyzed. Results The mean dose of left and right HC was(1 127±704)cGy,(1 173±762)cGy. The mean dose of left HH,HB and HT was(1 732±1029)cGy,(820±632)cGy,(423±366)cGy(P=0.000);while the mean dose of right HH, HB and HT was(1 985±1101)cGy,(837±531)cGy,(432±343)cGy(P=0.000).The exposed dose and the volume exposed in different dose of HH were obviously higher than those of HB and HT.The dose parameters of HH,HB and HT decreased in turn. The involvement of sphenoid sinus,ethmoid sinus and cavernous sinus correlated with high exposed dose of HC. Conclusions The exposed dose of HH,HB and HT was different in nasopharyngeal carcinoma patients treated with IMRT.The exposed dose of HH was the highest,which should be emphasized especially. The involvement of sphenoid sinus,ethmoid sinus and cavernous sinus suggest high exposed dose of HC.
