Introduction of image-guided stereotactic radiotherapy systems for small animals
10.3760/cma.j.issn.1004-4221.2018.02.022
- VernacularTitle:基于图像引导的小动物立体放疗系统介绍
- Author:
Gan QING
1
;
Jiazhou WANG
;
Weigang HU
;
Zhen ZHANG
Author Information
1. 200032,上海复旦大学医学院
- Keywords:
Small animal radiotherapy system;
Bioluminescence and Fluorescence;
Reconstruction
- From:
Chinese Journal of Radiation Oncology
2018;27(2):222-225
- CountryChina
- Language:Chinese
-
Abstract:
The theory and application of small animal radiotherapy models is critical for the research and development of radiobiology and clinical radiotherapy.Considering universality and cost effects,mouse models are widely used to explore the radiobiological mechanisms of cancerous and normal tissues.In recent years,there has been tremendous progress in image-guided stereotactic radiotherapy equipment for small animals,which could simulate the human radiotherapy process.This article introduces stereotactic radiotherapy systems for small animals guided by different imaging modalities,such as cone-beam computed tomography and magnetic resonance imaging,and then reviews small animal fluorescence imaging technology and summarizes the application of different bioluminescence and fluorescence imaging equipment in small animal imaging systems.Finally,we put forward the prospect of optimization direction of radiotherapy equipment for small animals in future.
