Advances in the mechanism of inflammatory response to radiation?induced brain injury

VernacularTitle:放射性脑损伤炎症反应机制的研究进展
Author: Xurui HUANG ¹ ; Haiwei HUANG
Author Information

1. 中山大学附属第一医院神经科国家临床重点专科与国家重点学科
Keywords: Radiation-induced brain injury; Microglia; Reactive oxygen species; Inflammatory mediators; Leukocytes
From: Chinese Journal of Radiological Medicine and Protection 2018;38(11):870-873
CountryChina
Language:Chinese
Abstract: The mechanisms of radiation-induced brain injury ( RBI) remain unclear. Currently a number of studies suggest that inflammatory response may play an important role in RBI. The production of reactive oxygen species, the release of inflammatory mediators, the interactions between neurons, glial cells, and pericytes, and the recruitment of peripheral leukocytes all contribute to the development of radiation-induced brain injury. This article reviews the research progress of the inflammatory response mechanism of radiation-induced brain injury.