Study on the influence of 125I seed implantation brachytherapy on QOL of patients with salivary gland malignant tumor
10.3760/cma.j.issn.0254-5098.2018.11.009
- VernacularTitle:放射性125I粒子组织间植入治疗不能手术唾液腺癌患者的生存质量分析
- Author:
Zhengwen LIU
1
;
Yan SHI
;
Shuming LIU
;
Haibo WANG
;
Yangfeng WU
;
Jianguo ZHANG
Author Information
1. 国家口腔疾病临床医学研究中心口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室
- Keywords:
QOL ( Quality of life );
Radioactive seeds;
Brachytherapy;
Salivary gland malignant tumor
- From:
Chinese Journal of Radiological Medicine and Protection
2018;38(11):846-850
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of 125I seed implantation brachytherapy on QOL of patients with salivary gland malignant tumor which couldn't be treated by conventional surgery and its influence factors. Methods 23 patients with malignant salivary gland cancer which couldn't be treated by conventional surgery were selected from Peking University School of Stomatology from 2013 to 2017. The patients were treated by 125I seed implantation brachytherapy. EORTC QLQ-C30 ( V3. 0 ) as well as QLQ-H&N35 QOL scale ( Chinese version) were used for the assessment of post-treatment QOL. Results The survival rate of one year and three years after treatment in 23 patients was 100％ and 67％, respectively. The score of the quality of life before and after treatment was 201. 48 and 199. 48, respectively. The difference was not significant after the test ( P>0. 05 ) . The level of total QOL and function score were relatively high. Among the influence factors, location of tumor significantly influenced QOL( F=9. 127,P<0. 05). Other factors still needed research based on larger sample. Conclusions 125I seed implantaion brachytherapy can better protect the head and neck function and maintain the quality of life of patients with salivary gland malignant tumor.
