Analysis of radiotherapy strategy for 110 breast cancer patients after R0 resection of local recurrence after radical mastectomy
10.3760/cma.j.issn.0254-5098.2018.09.006
- VernacularTitle:乳腺癌根治术后局部区域复发R0切除术后放疗110例分析
- Author:
Yue WANG
1
;
Huiru SUN
;
Xiangying MENG
;
Bing SUN
;
Santai SONG
;
Shikai WU
Author Information
1. 解放军307医院放疗科
- Keywords:
Breast cancer;
Local regional recurrence;
Radiotherapy
- From:
Chinese Journal of Radiological Medicine and Protection
2018;38(9):670-674
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of prognosis of consolidation radiotherapy for patients after R0 resection of local recurrence after radical mastectomy. Methods Totally 110 breast cancer patients with local recurrence receiving R0 resection were admitted and treated in our hospital from January 1st, 2003 to November 30th, 2015 were retrospectively analyzed. Results The median local progression time of 74 patients receiving consolidation radiotherapy ( 67.3％) was remarkably better than that of those without radiotherapy(36 patients, 32.7％), and the difference was statistically significant (χ2 =8. 526, P<0.05). Meanwhile, there was no statistically significant difference (P>0.05) of distance disease-free survival and overall survival between the radiotherapy group and the non-radiotherapy group. Multifactor analysis indicated that pseudo-adjuvant endocrine therapy (χ2 =7.541,95％CI:27.1％ -80.4％, P <0.05), DDFS(≥2 years vs. <2 years,χ2 =4.068,95％CI:101.4％ -267％,P<0. 05) and pseudo-adjuvant radiotherapy(χ2 =14.126, 95％CI:21.7％ -80.4％, P <0. 05 ) were the independent risk factors affecting the OS of patients with local recurrence after R0 resection. Conclusions For the patients with local recurrence after R0 resection of local recurrence, it is recommended that consolidation radiotherapy should be done and the radiation field should include the same side of the chest wall and clavicle area lymphatic drainage area.
