The feasibility study of gold nanoparticle composites (ssDNA-AuNPs) for the colorimetric detection of gamma radiation dose
10.3760/cma.j.issn.0254-5098.2018.08.010
- VernacularTitle:应用金纳米颗粒复合材料(ssDNA-AuNPs)比色检测γ射线照射剂量的可行性研究
- Author:
Yanchao SONG
1
;
Hongxing CUI
;
Qingzhao ZHANG
;
Changsong HOU
;
Yunyun WU
Author Information
1. 中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室
- Keywords:
Gold nanoparticle;
γ-rays;
Radiation dose;
Colorimetric detection
- From:
Chinese Journal of Radiological Medicine and Protection
2018;38(8):612-616
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a simple and convenient method and study the feasibility of using gold nanoparticle composites (ssDNA-AuNPs) for colorimetric detection of gamma radiation.Methods The composites ssDNA-AuNPs were prepared by applying the ssDNA to the surface of AuNPs,and then were irradiated with gamma ray with absorbed doses of 0,5,10,20,and 30 Gy,respectively.Subsequently the color change in the solutions were observed simultaneously with absorption spectra being measured.The linear relationship between the ratio of A625/A521 in the absorption spectrum and the absorbed dose was established.Results With the increase of radiation dose,the color of the solutions changed from wine-red to blue-violet gradually,the ratio of A625/A521 in absorption spectra had excellent liner response for absorbed dose ranging from 0 to 30 Gy,and the linear equation was A625/A521 =0.020 6 + 0.303 6 E(R2 =0.991 5).Conclusions The ssDNA-AuNPs synthesized in this experiment can be successfully used for colorimetric detection of gamma absorbed dose,and a simple and convenient method for detection of gamma radiation has been newly established.
