Development of methodology for dose quality audit of multi-leaf collimator in intensity modulated radiotherapy
10.3760/cma.j.issn.0254-5098.2018.02.007
- VernacularTitle:调强放疗多叶光栅野剂量质量核查方法研究
- Author:
Suming LUO
1
;
Hao WU
;
Xian XUE
;
Zhijian HE
;
Jilong YUAN
Author Information
1. 中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室
- Keywords:
Thermoluminescent dosimeter;
Film;
Intensity modulated radiotherapy;
Absorbed dose;
2D dose distribution passing rate;
Quality audit
- From:
Chinese Journal of Radiological Medicine and Protection
2018;38(2):115-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop the methodology for using TLDs and films to measure absorbed dose and 2D dose distribution produced by the multi-leaf collimator (MLC) in intensity modulated radiotherapy (IMRT),in order to provide the guidance on dose quality audit in IMRT.Methods A total of 30 different-typed accelerators were selected from 27 hospitals in Jiangsu,Sichuan,Hubei and Henan provinces,including 17 Varian accelerators,10 Elektas and 3 Simens.The same batch of films and TLDs were put in a 2 cm-thick solid plate for fixation and then loaded in a 15 cm × 15 cm × 15 cm polysyrene solid phantom supplied by International Atomic Energy Agency(IAEA) in terms of 90 cm SSD,19 cm depth,10 cm × 10 cm field at different doses.The standard dose curves wcrc established for film and TLD,respectively.The irradiated film was measured and then sent to the External Audit Group (EAG) in China.The TLD-and film-absorbed doses were compared with TPS-calculated doses.The 2D dose distribution on the IRMT MLC field was measured using films.The homogeneous phanton of 30 cn × 30 cm was scanned by CT and the image was transferred to the TPS.The IMRT was implemented with 6 Gy fractionated irradiation by placing a 25 cm × 25 cm film on the phantom surface at 95 cm SSD and at 5 cm depth.The irradiated film was sent to the IAEA dosimetry laboratory for measurement and calculation.2D dose distribution verification was conducted in thc same way consistent with the procedure of international multi-radiotherapy center.The 3 mm/3% passing rate was calculated for 2D dose distribution and compared with the film-measured and TPS calculated result.Results IAEA requires the relative deviation of TLD and film measured absorbed dose are with in ± 5%.The relative deviation of TLD-and filmmeasured to TPS-calculated absorbed dose was within the range of ±0.7%-± 8.5% and within ±0.3% ±7.8% in Jiangsu,Sichuan,Hubei and Henan provinces,respectively.IAEA requires the 3 mm/3% passing rate of film-measured 2D distribution to be 90%.The result of the present study were up to 94.0%.The verification result of 2D dose distribution were within 70.0%-99.9% in Sichuan,Jiangsu,Hubei and Henan provinces.Conclusions The adsorbed dose and 2D distribution can be audited using TLDs and films for MLC in IRMT.The method is scientific and applicable,economical and convenient for development of dose quality audit for a wide range of IRMT.