Dosimetric comparison between automated and manual volumetric modulated arc therapy planning for postoperative cervical cancer
10.3760/cma.j.issn.0254-5098.2018.01.006
- VernacularTitle:宫颈癌术后放疗中自动计划与人工计划的剂量学比较
- Author:
Junxiang WU
1
;
Shengwei KANG
;
Pei WANG
;
Bin TANG
;
Fan WU
;
Jinghui XU
;
Jie LI
Author Information
1. 四川省肿瘤医院放疗中心
- Keywords:
Automated VMAT plan;
Manual VMAT plan;
Postoperative cervical cancer;
Dosimetry
- From:
Chinese Journal of Radiological Medicine and Protection
2018;38(1):26-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare dosimetric parameters between automated and manualvolumetric modulated arc therapy(VMAT) plans in the treatment of postoperative cervical cancer patients,and to investigatethe feasibility and dosimetric advantage of the automated VMAT planning.Methods Automated and manual VMAT plans were generated with Pinnacle3 treatment planning system (TPS) for twenty-three postoperative cervical cancer patients,including eight patients in stage Ⅱ A and fifteen in stage Ⅱ B,respectively.The differences in D D95,conformity index (CI) and homogeneity index (HI) of target,as well as dose volume histogram (DVH) of organs at risk (OAR),planning time,average optimization time and monitor unit (MU) were compared between automated and manual VMAT plans.Results The average D CI and HI of automated VMAT plans were better than those of manual VMAT plans (t=4.65-14.92,P ＜0.05).There was no significant difference in D95 (P ＞0.05).The automated VMAT plans achieved better average dosimetric parameters on OARs compared with the manual VMAT plans (t =3.30-14.42,P ＜ 0.05).Automated VMAT plans had a significantly shorter planning time (72 min,t =3.85,P ＜ 0.05) and interruption frequency (twice,t =5.41,P ＜ 0.05) than manual VMAT plans.However,automated VMAT plans had a higher average MU than manual VMAT plans with an average MU of 819 ± 53 and 638 ± 41 for automated and manual VMAT plans,respectively.Conclusions It is feasible to generate automated VMAT plans with Pinnacle3 TPS for postoperative cervical cancer patients.The automated VMAT plans increase the plan quality and reduce the optimization time compare with manual VMAT plans.Automated technique also eliminates the influence of human factors on the plan quality.
