The clinical values of synovial volume measurement by MRI in patients with hemophilic arthropath receiving 32P radiation synovectomy
10.3760/cma.j.issn.1005-1201.2018.04.011
- VernacularTitle:血友病性关节病MRI滑膜体积测量评估放射性滑膜切除术疗效的价值
- Author:
Yincong DOU
1
;
Meixia LI
;
Lu ZHANG
;
Tianming CHENG
;
Pingchong LEI
;
Yinghui GE
Author Information
1. 450003,郑州大学人民医院河南省人民医院放射科
- Keywords:
Hemophilia;
Osteoarthropathy;
secondary hypertrophic;
Clinical efficacy;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2018;52(4):291-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of eynovial membrane volume measurement by MRI in patients with hemophilic arthropathy receiving radionuclide synoviectomy. Methods Forty two patients,total 63 diseased joint,who hospitalized in the hemophilia diagnosis and treatment center of Henan Province People's Hospital were enrolled in the study after receiving both enhanced an non enhanded MRI, from May 2011 to January 2015.Sixteen patients(21 joints)were treated with 32P radionuclide synoviectomy (PRS)and followed up.The synovial membrane volume were evaluated by enhanced and non enhanded MRI before and after PRS. All data were analyzed by t test. Results The synovial membrane volume had no statistical difference by using the non enhanced(3 104.38±60.19)mm3and enhanced(2 995.19±59.14)mm3 MRI scans (t=-1.369, P=0.191). The synovial membrane volume post PRS (2 479.45 ± 46.48)mm3much lower than that before PRS (2 983.30 ± 42.87) mm3(t=7.831,P=0.000). The magnetic resonance enhanced range after PRS (0.92 ± 0.06) was significantly lower than that before treatment (1.17 ± 0.07) (t=2.108, P=0.048). Conclusion Synovial membrane volume and magnetic resonance enhanced range are important index to predict clinical efficacy of PRS.
