Safety and effectiveness of prostatic arterial embolization for the treatment of benign prostatic hyperplasia
10.3760/cma.j.issn.1005-1201.2018.03.013
- VernacularTitle:超选择性前列腺动脉栓塞术治疗巨大前列腺增生所致下尿路阻塞的价值
- Author:
Bing YUAN
1
;
Jinlong ZHANG
;
Kai YUAN
;
Guodong ZHANG
;
Jieyu YAN
;
Maoqiang WANG
Author Information
1. 解放军总医院介入放射科
- Keywords:
Prostatic hyperplasia;
Angiography,digital subtraction;
Prostatic arterial embolizatio;
Lower urinary tract symptoms
- From:
Chinese Journal of Radiology
2018;52(3):223-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness and safety of prostatic arterial embolization as a primary treatment for patients with lower urinary tract symptoms as a result of large benign prostatic hyperplasia.Methods This was a prospective,single-center study enrolling 64 patients with prostates>80 ml from January 2010 to December 2013.Prostatic arterial embolization was carried out using a combination of 50 μm and 100 μm particles.Clinical follow up was carried out using the International Prostate Symptom Score, quality of life, peak urinary flow, postvoid residual volume, International Index of Erectile Function Short Form, prostate-specific antigen, and prostatic volume at 1, 3, 6 month following embolization, the parameters were compared by using t test. Results Prostatic arterial embolization was technically successful in 60 of 64 patients (93.8%). Follow-up data were available for 60 patients with a mean of 18 months,a total of 42 patients had completed the follow up at 24 months after prostatic arterial embolization. A clinical improvement,defined as reduction of International Prostate Symptom Score and increase of peak urinary flow, at 1 month, 3 months, 6 months, 12 months and 24 months, was achieved in 95.0%(57/60), 95.0%(57/60),93.3%(56/60),92.6%(50/54) and 90.5%(38/42), respectively. There was an improvement in terms of mean International Prostate Symptom Score, mean quality of life, mean peak urinary flow, mean post-void residual volume and prostatic volume were significantly different with respect to baseline(all P<0.05).No serious complications occurred.Conclusion Prostatic arterial embolization appears to be a safe and effective treatment method for patients with lower urinary tract symptoms as a result of large benign prostatic hyperplasia.
