The assessment of the left atrial myocardial fibrosis of atrial fibrillation with late Gadolinium enhancementMRI
10.3760/cma.j.issn.1005-1201.2018.03.003
- VernacularTitle:延迟增强MRI对心房颤动患者左心房心肌纤维化的评估价值
- Author:
Lina DOU
1
;
Chunai HU
;
Weihong SUN
;
Guangchao LI
;
Jupan HOU
;
Lulu LYU
;
Bing HAN
;
Xianjin LI
;
Yibing SHI
;
Jingming HAO
Author Information
1. 221009,徐州市中心医院影像科
- Keywords:
Atrial fibrillation;
Magnetic resonance imaging;
Comparative study
- From:
Chinese Journal of Radiology
2018;52(3):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of 2 dimension late Gadolinium enhancement MRI (LGE-MRI) technique for the evaluation of atrial myocardial fibrosis in patients with atrial fibrillation. Methods Forty-nine cases of atrial fibrillation in our hospital from March 2015 to December 2016 were retrospectively collected. The LGE-MR was acquired by the Siemens 3.0 T MR machine before the catheter ablation.The findings of LGE-MR were evaluated by two experienced doctors. The left atrium(LA)were manually segmented into 8 regions in axial view.All patients were classified into 4 stages based on the extent of enhancement, stage 0: absence of enhancement, stage Ⅰ: enhancement appeared in minimal two consecutive slices in single region,stageⅡ:enhancement in two regions,stageⅢ:enhancement in three or more regions. All electroanatomic maps were obtained after electrical conversion during catheter ablation. The Kappa test was used to assess the consistency of LGE-MRI left atrial myocardial fibrosis and CARTO system of the left atrial endocardial voltage reconstruction. Results Forty-nine cases of atrial fibrillation with LGE-MRI and CARTO were included. There were 17 cases of atrial fibrosis stage 0,10 cases of stageⅠ,11 cases of stageⅡ,11 cases of stageⅢaccording to LGE-MRI findings;There were 17 cases of atrial fibrosis stage 0,19 cases of stageⅠ,12 cases of stageⅡ,11 cases of stage Ⅲ with reference to CARTO findings. The diagnostic accuracy of the LGE-MRI atrial fibrosis was 81.6%(40/49),of which the correlation was good(Kappa= 0.751,P<0.001). Conclusions LGE-MRI can accurately assess the degree of left atrial myocardial fibrosis in patients with atrial fibrillation,help to select the proper candidate and strategy in catheter ablation.
