Analysis of pregnancy outcome and mother-child related concerns in patients with Takayasu arteritis
10.3760/cma.j.issn.1007-7480.2018.03.009
- VernacularTitle:大动脉炎妊娠风险研究分析
- Author:
Zhiqin LI
1
;
Zhaohui ZHENG
;
Linxuan PANG
;
Wanglei DU
;
Zhenbiao WU
;
Ping ZHU
Author Information
1. 空军军医大学第一附属医院西京医院临床免疫科
- Keywords:
Takayasu arteritis;
Pregnancy;
Pregnancy complications
- From:
Chinese Journal of Rheumatology
2018;22(3):186-190
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess pregnancy outcome and pregnancy related concerns in Takayasu arteritis (TA) patients.Methods We analyzed 68 female patients with TA retrospectively from Xijing hospital.Data on the number of pregnancies,births and pregnancy outcomes before and after disease onset were retrieved from medical charts,patient questionnaires and the department of Obstetrics in Xijing Hospital.Data on pregnancy related concerns were gathered from patient questionnaires.Results Altogether,68 women in the TA study cohort had 106 pregnancies,73 (in 41 patients) before disease onset and 33 (in 28 patients) after disease onset.There were no difference in the frequencies of miscarriages,induced abortions and maternal complications before and after TA onset.Pregnancy related hypertension was seen in 4.7％ of the TA patients compared to 2.0％ (x2=1.238,P＞0.05) of the reference cohort from the department of Obstetrics in Xijing Hospital and preeclampsia/eclampsia in 4.7％ of the TA patients compared to 2.8％ of the reference cohort (x2=1.835,P＞0.05).The mean gestational age at delivery in pregnancies after TA onset was (37±6) weeks compared to (39±4) weeks in the reference cohort (x2=14.665,P＜0.01).Caesarian sections were more frequent in deliveries after TA onset (36％) than in the reference cohort (15％) (x2=13.322,P＜0.01).86％ of the TA patients had pregnancy related concerns.Of these concerns,72％ was about passing the disease to offsprings.Conclusion In this population based TA cohort,the maternal and fetal outcomes are favorable.Pregnancy related concerns are very popular in TAK patients.
