Perinatal outcomes of thoraco-amniotic shunting for severe primary fetal hydrothorax
10.3760/cma.j.issn.0529-567x.2018.09.002
- VernacularTitle:胸腔-羊膜腔分流术应用于严重胎儿原发性胸腔积液的围产儿结局分析
- Author:
Xing WEI
1
;
Meng MENG
;
Gang ZOU
;
Fenhe ZHOU
;
Yingjun YANG
;
Yun ZHANG
;
Meizhen YUAN
;
Fengyu WU
;
Luming SUN
Author Information
1. 同济大学附属第一妇婴保健院产前诊断中心暨胎儿医学科
- Keywords:
Pleural effusion;
Hydrops fetalis;
Catheterization;
Decompression;
Pregnancy outcome
- From:
Chinese Journal of Obstetrics and Gynecology
2018;53(9):590-594
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and perinatal outcomes of thoracoamniotic shunting in the treatment of fetuses with severe primary hydrothorax. Methods 22 cases of suspected severe primary fetal hydrothorax which underwent thoraco-amniotic shunting in Shanghai First Maternity and Infant Hospital,Fetal Medicine Unit and Prenatal Diagnosis Center from January 2012 to December 2017 were analyzed retrospectively. Hydrothorax associated with structural or chromosomal abnormalities, infections and immune fetal hydrops were excluded. Results Totally ,28 shunts were placed in 22 fetuses. The median gestational age at TAS was 31.3 weeks. Preterm membrane rupture within 7 days after the procedure occurred in 9.1％(2/22) cases. Catheter displacement occurred in 18％(4/22) cases. The interval from shunting to delivery was 26.0 days. One fetus ended in induced abortion; 21(95％,21/22) babies were born alive, and their median gestational age at delivery was 34.4 weeks. 62％(13/21)newborns required ventilator supports; 4 neonatal deaths were attributed to pulmonary hypoplasia. The overall perinatal survival rate was 81％(17/21). The perinatal survival rate with hydrops and without hydrops were 10/13 and 7/8 respectively. Conclusion Thoraco-amniotic shunting is a safe procedure for intrauterine therapy and could improve the perinatal outcomes of severe primary fetal hydrothorax.
