The predictive validity of fetal/embryonic heart monitoring during the first trimester in assessing the pregnancy outcomes
10.3760/cma.j.issn.1004-4477.2018.11.014
- VernacularTitle:超声监测早孕期胚胎心率对妊娠结局的预测价值
- Author:
Xiaoping GONG
1
;
Guanjie WANG
;
Haifei WANG
;
Xiaoxiao KONG
;
Tian YANG
;
Xiaorui LIU
;
Yunyun CAO
Author Information
1. 200030,上海交通大学医学院附属国际和平妇幼保健院超声科
- Keywords:
Ultrasonography;
Heart rate,fetal;
First trimester;
Pregnancy outcome
- From:
Chinese Journal of Ultrasonography
2018;27(11):982-985
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pregnancy outcomes in women whose fetal/embryonic heart rate( FHR) were below 120 beats per minute( bpm) before 8 weeks pregnancy and determine the predictive value of FHR in pregnancy outcome . Methods The laboratory examinations ,clinical data and clinical history of the pregnant women whose FHR were below 120 bpm before 8 weeks pregnancy were retrospectively analyzed . Results When gestational age(GA) was less than 8 weeks ,pregnancy loss was observed in 11 .0% ( 110/998 ) cases with an FHR less than or equal to 120 bpm ,and pregnancy loss occurred in all the cases ( 23/23) with an FHR less than or equal to 70 bpm . The proportions of first trimester loss were 86 .4% (19/22) for pregnancies with an FHR of 71 －80 bpm ,75 .7% (28/37) for pregnancies with an FHR of 81－90 bpm ,25 .5% (14/55) for pregnancies with an FHR of 91 －100 bpm , 6 .3% (13/208) for pregnancies with an FHR of 101 －110 bpm ,and 2 .0% (13/653) for pregnancies with an FHR of 111 －120 bpm .ROC analysis showed that the best cut-off value to predict adverse pregnancy outcomes was an FHR of 94 bpm . The area under the ROC curve was 0 .906 ( P ＜ 0 .0001 ) and its sensitivity and specificity values were 97 .86% and 71 .43% respectively . Conclusions Fetal/embryonic heart monitoring before 8-weeks pregnancy can be an effective predictor for early pregnancy outcome . The best cut-off value to predict adverse pregnancy outcomes is an FHR of 94 bpm .
