Study on diagnosis of fetal congenital heart disease by echocardiography and integrated management in a single center in northwestern region of China
10.3760/cma.j.issn.1004-4477.2018.09.006
- VernacularTitle:西北地区单中心胎儿先心病超声诊断与一体化管理的初步研究
- Author:
Yin WANG
1
;
Zheng WANG
;
Peng XU
;
Wenjuan YANG
;
Minjuan ZHENG
;
Jianfang ZHANG
;
Ting ZHU
;
Shen PANG
;
Jun LI
Author Information
1. 空军军医大学第一附属医院超声医学科 陕西省胎儿先天性心脏病超声诊断中心
- Keywords:
Echocardiography;
Congenital heart disease;
Fetal;
Integrated management
- From:
Chinese Journal of Ultrasonography
2018;27(9):759-765
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the detection rate ,types ,accompanying abnormalities and prognosis of fetal congenital heart disease(CHD) in a single center in northwest China ,in order to set up a foundation for further studying the epidemiological characteristics of fetal CHD and integrated management of fetal CHD in the prenatal and postnatal . Methods A total of 2725 CHD in 45015 fetus diagnosed by fetal echocardiography were enrolled . The fetal CHD detection rate and the composition ratio were calculated . Follow-up results between the simple CHD and complex CHD were analyzed . Results The detection rate of fetal CHD in our center was up to 6 .1% . There were 1589 cases of complex CHD ,accounting for 58 .3% in all the fetal CHD ,of which the most common type was single ventricle ,followed by tetralogy of Fallot , atrioventricular septal defect and double outlet right ventricle ;Simple CHD 1136 cases ,accounting for 41 .7% in all the fetal CHD ,the most common type was ventricular septal defect . The number of abortion cases ,intrauterine and postnatal natural deaths of fetal CHD accounted for 60 .3% ( 1357/2251) of the total follow-up ,of which complex CHD and chromosomal abnormalities accounting for the majority . 68 cases of CHD underwent surgical treatment after birth ,of which complex CHD were predominant . 37 cases of simple CHD spontaneous closure and 27 cases of simple CHD genetic test results were abnormal . Conclusions The detection rate of CHD in this group is relatively high ,which is related to the prenatal diagnosis consultation center . Fetal complex CHD is more common while the prognosis is worse than simple CHD . Prenatal and postnatal integrated management of fetal CHD has important clinical value in early treatment of complex CHD .