Evaluation of left ventricular systolic function and synchronicity in patients with maintenance hemodialysis by layer-specific strain
10.3760/cma.j.issn.1004-4477.2018.05.003
- VernacularTitle:分层应变技术评价维持性血液透析患者左心室收缩功能及同步性的价值
- Author:
Jingjing HEI
1
;
Changhua WEI
;
Haohui ZHU
;
Yang LI
;
Xiao DING
;
Chunhong GU
;
Jianjun YUAN
Author Information
1. 450003,郑州大学人民医院超声科
- Keywords:
Echocardiography;
Renal dialysis;
Ventricular function,left;
Layer-specific strain
- From:
Chinese Journal of Ultrasonography
2018;27(5):380-384
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the systolic function and synchronicity of left ventricle ( LV ) in patients with maintenance hemodialysis( MHD) by layer-specific strain. Methods Forty-three patients with MHD and 48 healthy controls were studied. Three consecutive cardiac cycles two-dimensional dynamic images including standard LV apical two-chamber,long-axis and four-chamber views and LV short-axis views at the levels of basal,middle and apical were acquired. A quantitative software called EchoPAC was used to analyze longitudinal strain(LS) and circumferential strain(CS) of these six dynamic images and peak strain dispersion ( PSD) was automatic computed by the software. The difference of these parameters between the two groups and the correlation between PSD and other parameters were studied. Results Parameters of global layer-specific strain: compared with the control group, global LS and CS of subendocardial,midmyocardial,epicardial and full-thickness myocardium layers were decreased in the MHD group ( P ＜0.01). Parameters of segmental layer-specific strain:LS of 3 layers and full-thickness in basal, middle,apical segments were lower in MHD group than those in control group ( P ＜0.001). CS of 3 layers and full-thickness in middle,apical segments were lower in MHD group than those in control group ( P ＜0.05). There was no significant difference in CS of 3 layers and full-thickness in basal segment between two groups( P ＞0.05). Parameters of synchronicity:PSD of MHD group was larger than that of control group ( t ＝6.094, P ＜0.001). PSD was positively correlated with longitudinal strain of full-thickness (GLS) in MHD group ( rs＝0.478, P ＝0.039). Conclusions Layer-specific strain can noninvasively and accurately quantitate left ventricular systolic function and synchronicity in patients with MHD.
