Meta analysis of left ventricular normal reference value in echocardiographic measurements for racial heterogeneity
10.3760/cma.j.issn.1004-4477.2018.05.001
- VernacularTitle:左心室超声心动图测量参考值种族差异性的 Meta 分析
- Author:
Yiping LI
1
;
Lixue YIN
;
Mei ZHANG
;
Sijia WANG
;
Guihua YAO
;
Yan DENG
;
Shuang LI
;
Yun ZHANG
Author Information
1. 西南医科大学
- Keywords:
Echocardiography;
Ventricular function,left;
Reference values;
Heterogeneity;
Meta-analysis
- From:
Chinese Journal of Ultrasonography
2018;27(5):369-374
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the heterogeneity of the left ventricular reference value in echocardiography mesurements by Meta analysis. Methods A literature retrieval in PubMed,Embase, Medline and other databases from January 2005 to September 2017 related to left ventricular normal reference value in healthy adults was performed. Cohrane′s Q test was used to test the heterogeneity,and I2 was used as a statistic for the description of heterogeneity. Subgroup analysis,sensitivity analysis and Meta regression were used to analyze the sources of heterogeneity. Results The Meta analysis enrolled 9 studies including 5 933 normal cases. The heterogeneity test showed that the left ventricular normal reference value of echocardiography was highly heterogeneous among the studies. In subgroup analysis, some measurements′ heterogeneity were significantly reduced. Meta regression analysis showed that the contribution of racial specificity to heterogeneity was relatively high in some measurements. Conclusions The heterogeneity of left ventricle is mainly related to racial specificity,but it cannot fully explain the heterogeneity between studies. Further studies are needed to demonstrate the involved factors of heterogeneity of left ventricular normal reference values.
