Quantitative analysis of myocardial perfusion in patients with coronary slow flow by real-time myocardial contrast echocardiography
10.3760/cma.j.issn.1004-4477.2018.04.001
- VernacularTitle:实时心肌超声造影定量评价冠脉慢血流患者心肌血流灌注
- Author:
Yumeng XING
1
;
Dehong KONG
;
Yongle CHEN
;
Jing SHI
;
Yan YAN
;
Haiyan CHEN
;
Xianhong SHU
;
Cuizhen PAN
Author Information
1. 复旦大学附属中山医院 上海市影像医学研究所 上海市心血管病研究所心超室
- Keywords:
Echocardiography;
Coronary disease;
Myocardial microcirculation;
Myocardial perfusion
- From:
Chinese Journal of Ultrasonography
2018;27(4):277-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical value of real-time myocardial contrast echocardiography ( RT-MCE) on quantitative assessing myocardial perfusion in patients with coronary slow flow ( CSF ) . Methods CSF group contained 14 patients with CSF and 15 cases with normal coronary angiography ( CAG) were involved as control group . The 2D echocardiography and RT-MCE images from standard 3 apical views ( 4-chamber ,2-chamber ,and long-axis) were acquired . All images were digitally stored on hard disks for offline analysis by QLab software . The RT-MCE parameters included myocardial blood volume ( A) , myocardial blood veloity ( β) ,myocardial blood flow ( MBF) were used to predict the impairment of myocardial perfusion in the two groups . Results In CSF group ,the value of β and MBF in abnormal segments were significantly lower than those in normal segments ( P < 0 .001) . There was no significant difference of A between the abnormal segments and the normal segments in CSF group ( P > 0 .05 ) . Compared to the control group ,the value of β and MBF were significantly lower in abnormal segments of CSF group( P < 0 .001) . Comparing the normal segments of two groups ,there was no significant difference in the values of A ,β and MBF ( P > 0 .05) . ROC curve analysis showed the AUC of β was the biggest ( AUC = 0 .867 , P < 0 .001 ) , and when the cut-off value was 1 .34 , the impairment of myocardial microcirculation was best predicted ( sensitivity ,79 .6％ ;specificity ,77 .4％ ) . Conclusions The myocardial perfusion in patients with CSF can be appraised by RT-MCE quantitatively . The value of β can identify the early impairment of myocardial microcirculation perfusion in patients with CSF and has the promising prospect of clinical diagnosis .
