Prospective study of anterior uterocervical angle for prediction of preterm birth in second trimester with transperineal ultrasound
10.3760/cma.j.issn.1004-4477.2017.12.015
- VernacularTitle:经会阴部超声测量孕中期子宫宫颈前角与宫颈长度对预测早产的对比研究
- Author:
Yan DING
1
;
Xinmei ZHAO
;
Lei CHEN
;
Chunyan WU
;
Jinqi MA
;
Ying LI
Author Information
1. 南京医科大学附属无锡人民医院超声医学科
- Keywords:
Ultrasonography;
Anterior uterocervical angle;
Premature birth;
ROC curve
- From:
Chinese Journal of Ultrasonography
2017;26(12):1084-1087
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the possibility and value of the anterior uterocervical angle ( ACA) and cervical length for prediction of preterm birth in second trimester with the transperineal ultrasound . Methods This study retrospectively reviewed the relevant medical records of single birth primiparas undergoing prenatal ultrasonographic evaluation in Wuxi People′s Hospital Affiliated to Nanjing Medical University from January 2016 to December 2016 . The pregnant women were divided into preterm group and term group according to the pregnancy outcomes ( with or without preterm birth) . The ACA and cervical length of these pregnancies were measured in the second trimester ( between 22 -24 weeks gestation) with the transperineal ultrasound . Results A total of 1064 pregnant women were enrolled in the study ,with 84 cases in preterm group ( 78 .9% ,84/1064) and 980 cases in term group ( 92 .11% ,980/1064) . Age of women in the two groups had no statistics difference( P =0 .86) . The mean ACA and cervical length of preterm group were ( 112 .48 ± 15 .83)° and ( 30 .94 ± 6 .32) mm ,and the mean ACA and cervical length of term group were (103 .52 ± 13 .78)° and (37 .28 ± 6 .74)mm ,there were statistically difference( P <0 .05) . The area under ROC curve of the ACA was 0 .882 ,of the cervical length was 0 .664 ,the corresponding cutoff value were 113°and 27 mm ,respectively . The sensitivity of the ACA and cervical length in predicting preterm birth were 86 .90% and 71 .43% ,the specificity were 75 .00% and 62 .14% ,the accuracy were 75 .94% and 62 .66% ,respectively . Conclusions The ACA is an objective and effective indicator to predict preterm birth in the second trimester with transperineal ultrasound . The diagnostic value of measuring the ACA is better than that of measuring the cervical length in the same period .