Correlation between peripheral nutrient artery and expression of C-erbB-2 in breast invasive ductal carcinoma
10.3760/cma.j.issn.1004-4477.2017.12.013
- VernacularTitle:乳腺浸润性导管癌肿块周边滋养动脉与C-erbB-2表达的关系
- Author:
Guozhu WU
1
,
2
;
Hua HONG
;
Ruiqiang GUO
Author Information
1. 430060 武汉大学人民医院超声科
2. 内蒙古自治区人民医院超声科 ,呼和浩特010017
- Keywords:
Ultrasonography;
Carcinoma,ductal,breast;
Peripheral nutrient artery of tumor;
C-erbB-2
- From:Chinese Journal of Ultrasonography
2017;26(12):1074-1078
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relation between peripheral nutrient artery and expression of C-erbB-2 in breast invasive ductal carcinoma(IDC) . Methods The peak systolic velocity(PSV) and resistive index ( RI ) of peripheral nutrient artery of tumor in 122 cases with breast IDC and 138 cases with fibroadenoma which proved by operation and pathology were analyzed retrospectively . The C-erbB-2 was measured by immunohistochemical test ,according to the results of immunohistochemical examination ,the masses were divided into negative group( -) ,weakly positive group( + ) ,positive group( + + ) and strong positive group( + + + ) . The relationship between the classification of C-erbB-2 expression and the two factors of peripheral nutrient artery in breast tumor mass were analysed . Results The PSV of trophoblastic artery in IDC group was ( 20 .99 ± 8 .14 ) cm/s , RI 0 .66 ± 0 .07 , the PSV of trophoblastic artery in fibroadenoma group was (15 .56 ± 3 .68)cm/s ,RI 0 .66 ± 0 .07 ,there was significant statistically difference in peripheral nutrient artery of tumor between the breast IDC and fibroadenoma( P < 0 .001) . The RI and PSV of the peripheral nutrient artery in IDC were correlated to the classification of C-erbB-2 expression ( r=0 .323 ,0 .360 ,respectively) ,there was no correlation between the RI and PSV of peripheral nutrient artery in fibroadenoma and the classification of C-erbB-2 expression ( r = 0 .001 ) . Conclusions The spectrum form of peripheral nutrient artery in IDC is high speed and high resistance . The RI and PSV of the peripheral nutrient artery in IDC are correlated to the classification of C-erbB-2 expression .
